BoltzFold
Queue Protein folding predictions, monitor progress, and download structures.
commoditize protein folding
One API for ESMFold (fast), OpenFold (accurate, coming), and Boltz-2 (protein-ligand). EU-hosted, privacy-first, reproducible by default.
Join the API waitlist
Tell us how you plan to use the BoltzFold API and we'll reach out when seats open.
Used by early teams at
How it works
1) Submit
POST /v1/predict with a FASTA (and SMILES for ligand). Or use the web UI.
2) We route
Auto-select the best model for speed vs accuracy (or pin one). Jobs run asynchronously on dedicated GPUs.
3) Download
Get .pdb/.cif, confidence (pLDDT/PAE), and affinity (Boltz-2). Every job includes a reproducibility manifest.
Why teams switch to us
Multi-model, one endpoint
ESMFold fast, OpenFold accurate (soon), Boltz-2 for protein–ligand. Route automatically or have full control if you want.
Predictable costs
Per-residue pricing, cache re-use, and budget guardrails.
Private by design
EU data residency, zero-retention mode, audit logs, signed manifests.
Developer-first
Simple REST, Python/JS SDKs, webhooks, standardized outputs.
What's under the hood
- Models: ESMFold (fast), OpenFold (accurate, coming), Boltz-2 (protein–ligand)
- API: Async jobs, webhooks, standardized artifacts (PDB/mmCIF, pLDDT/PAE, affinity)
- Reproducibility: model+weights hash, MSA DB versions, seeds, GPU type
- Privacy: EU regions, zero-retention, customer-managed keys (roadmap)
FAQ
How fast are results?
Minutes. ESMFold often < 2 min; OpenFold 3–10; Boltz-2 5–15 depending on length/steps.
Is it license-safe for commercial use?
Yes — the models/weights we serve (ESMFold, OpenFold, Boltz-2) permit commercial use with attribution where required.
Can I pick the model?
Yes. Use mode=auto or pin a backend explicitly.
Where does my data live?
EU by default. Zero-retention mode and VPC/on-prem options on request.
For investors
We're standardizing structure prediction into a developer-first primitive: a license-clean, EU-native folding substrate that routes across models and returns publishable outputs. An API for developers and a web UI for researchers.